Coronary Disease
ACS patients with several metabolic risk factors may benefit most from PCSK9 inhibitors
Co-prescribed PDE5 inhibitors and nitrates not tied to adverse outcomes
Serious mental illness tied to increased CV risk, starting in young adulthood
CT as effective as invasive angiography for guiding treatment of stable chest pain
Conflicting periprocedural MI definitions impact clinical practice, research
Pilot trial shows potential benefit of stem-cell therapy in microvascular dysfunction
Apixaban plus P2Y12 inhibitor likely best for AF after ACS or PCI
Whether treated with CABG or PCI, heavily calcified lesions tied to higher mortality
Early surgery outperforms conservative management in asymptomatic severe aortic stenosis
External support device for SVG grafts in CABG surgery shows promise
Carefully selected patients can go home the day after PCI for STEMI
Extracoronary vascular events likely rare after spontaneous coronary artery dissection
Time from stopping blood thinner to CABG can be safely shortened
Bypass still better than stenting in severe heart disease – study
Coronary calcium score alone of limited value in younger patients with suspected CAD
Adding rivaroxaban to aspirin may help some CAD, PAD patients live longer
Men and women benefit equally from early aspirin withdrawal following PCI
Better outcomes with invasive strategy if anatomic complete revascularisation is possible
PCI for chronic total occlusion more successful after coronary CTA
Subgroup of patients with high heart rate response and coronary artery disease benefit from CPAP
Lower burden of high-risk atherosclerotic plaques in psoriasis patients treated with biologics
PCI for in-stent chronic total occlusion shows in-hospital success
Benefits of multivessel PCI unclear in patients with NSTEMI and cardiogenic shock
Bleeding, vascular complication rates lower when transradial PCI replaces transfemoral PCI
Higher bleeding risk in women after PCI mostly due to baseline sex differences
No age cap for lipid-lowering therapy
Cancer patients have higher readmission rates for heart attack, bleeding after PCI
Extra imaging reveals cause of MINOCA in women
Ticagrelor not superior to clopidogrel after elective PCI
Long-term mortality after coronary-artery occlusion may not depend on recanalization status
Benzodiazepines given for ACS anxiety, pain may trigger posttraumatic stress symptoms
Calcium chloride during CABG curbs subsequent atrial fibrillation
DASH-diet intervention might slow progression of nonobstructive coronary atherosclerosis
Higher levels of diet-derived antioxidants don’t protect against heart disease
Trimetazidine after successful PCI not associated with fewer cardiac events
Low-dose colchicine reduces CV death and ischaemic events in coronary disease
Rivaroxaban protects limbs and ischaemic events in CAD-PAD patients
Reduced progression of coronary atherosclerosis with icosapent ethyl
Mortality lower after coronary bypass surgery than after percutaneous interventions
Intravascular lithotripsy safely treats severely calcified coronary-artery disease
Fewer adverse events with ticagrelor monotherapy after 3 months DAPT
TWILIGHT sub-study: same outcomes for diabetes patients
TWILIGHT sub-study: complex PCI patients
Apixaban in AF patients with recent ACS/PCI: Drop aspirin after 30 days
Radial artery best for second bypass
PCI and CABG are equal in left main CAD
TAILOR-PCI misses endpoint but still provides valuable insights
Drop aspirin after 3 months in non-STEMI ACS patients on dual antiplatelet therapy
Immediate coronary angiography after cardiac arrest does not improve survival
Complete revascularisation for obstructive non-culprit lesions with vulnerable plaque
Colchicine: no difference in peri-procedural cardiovascular events 30 days post-PCI
Intra-aortic balloon pump better than Impella: new observational data
ISCHEMIA trial: Invasive treatment only better for angina burden
