Dementia

Biogen pulls application for Alzheimer’s drug in Europe

22 April, 2022 19:23

AAN 2022 Highlights Podcast

Presented By

Robert van den Heuvel, Medicom

Conference

AAN 2022

19 April, 2022 22:42

Late-onset alcohol abuse may signal dementia

Journal

Journal of Alzheimer's Disease

18 April, 2022 23:27

Stroke treatment effective for individuals with disability or dementia: AHA/ASA

Journal

Stroke

8 April, 2022 22:10

Eisai seeking accelerated FDA review of Alzheimer’s drug after U.S. coverage decision

8 April, 2022 21:29

Study links drowsiness in Alzheimer’s to wake-promoting brain regions

Journal

JAMA Neurology

7 April, 2022 15:24

Computational model of Alzheimer’s links symptoms, brain anatomy, mental processing

Journal

Nature Communications

5 April, 2022 22:40

Atrial myopathy may contribute to dementia risk

Journal

JAMA

22 March, 2022 17:28

Biogen publishes Alzheimer’s drug data in lesser-known journal

Journal

Journal of Prevention of Alzheimer's Disease

18 March, 2022 17:38

Tau buildup in brain tied to psychosis, more rapid decline in Alzheimer’s disease

Journal

Translational Psychiatry

11 March, 2022 23:11

Poor score on a simple memory test tracks with Alzheimer’s biomarkers

Journal

Neurology

1 March, 2022 18:50

Certain antihypertensive meds might help prevent cognitive decline

Journal

JAMA Network Open

11 February, 2022 15:59

Alzheimer’s-like changes seen in COVID-19 patients’ brains

Journal

Alzheimer's & Dementia; bioRxiv; Preprints with The Lancet

4 February, 2022 23:44

Reduced risk of Alzheimer’s disease in CHIP carriers

Presented By

Dr Hind Bouzid, Stanford University, CA, USA

Conference

ASH 2021

4 February, 2022 10:49

Drugs that boost neurotrophic support might be helpful in early dementia

Journal

JAMA Neurology

31 January, 2022 23:08

Dementia risk increased after ischemic stroke

Journal

JAMA Neurology

28 January, 2022 16:15

After initial dip, dementia risk rises with diabetes duration

Journal

Age and Ageing

12 January, 2022 16:04

After initial dip, dementia risk rises with diabetes duration

Journal

Age and Ageing

12 January, 2022 16:04

Post-traumatic amnesia, chronic vascular lesions risk factors for Alzheimer’s after TBI

Journal

Alzheimer Disease & Associated Disorders

6 January, 2022 20:41

Senescent cells with neurofibrillary tangles identified as potential Alzheimer’s treatment target

Journal

Nature Aging

23 December, 2021 01:32

Cataract extraction linked to lower dementia risk

Journal

JAMA Internal Medicine

15 December, 2021 22:13

Online self-test detects mild cognitive impairment shift to dementia sooner than MMSE

Journal

Alzheimer's Research and Therapy

13 December, 2021 22:18

Sildenafil use tied to reduced risk of Alzheimer’s

Journal

Nature Aging

10 December, 2021 22:01

Researchers find ‘promising’ blood biomarkers for cognitive decline in dementia

Journal

JAMA Neurology

3 December, 2021 18:27

Impaired blood-brain barrier may underlie Parkinson’s disease progression

Journal

Neurology Genetics

26 November, 2021 21:59

Amyloid-related imaging abnormalities seen in about 40% of aducanumab users in clinical trials

Journal

JAMA Neurology

25 November, 2021 16:28

Biogen’s Alzheimer’s drug gets negative European panel vote

17 November, 2021 15:23

Premenopausal oophorectomy tied to increased risk of cognitive impairment

Journal

JAMA Network Open

16 November, 2021 22:46

Biogen says Aduhelm lowers levels of second protein associated with Alzheimer’s

12 November, 2021 15:27

MEF2 expression linked to cognitive resilience in Alzheimer’s disease

Journal

Science Translational Medicine

9 November, 2021 21:32

Tau replication in local brain regions, not spread between regions, drives Alzheimer’s pathology

Journal

Science Advances

3 November, 2021 22:05

Brain white matter connectivity disrupted in symptomless, early-onset Alzheimer’s

Journal

Radiology

22 October, 2021 23:51

Blood GFAP a sensitive biomarker for early Alzheimer’s disease

Journal

JAMA Neurology

18 October, 2021 22:39

Tau accumulation in brain likely best biomarker of short-term cognitive decline in Alzheimer’s

Journal

Molecular Psychiatry

13 October, 2021 22:54

Diuretic shows promise for dementia prevention and treatment

Journal

Nature Aging

12 October, 2021 17:14

Menopausal hormone therapy not linked to dementia risk

Journal

The BMJ

7 October, 2021 23:04

Methylphenidate safe, effective for apathy in Alzheimer disease

Journal

JAMA Neurology

5 October, 2021 23:34

Study confirms link between dementia risk and eye disorders

Journal

British Journal of Ophthalmology

5 October, 2021 17:19

Not all amyloid-beta assays and methods perform equally well

Journal

JAMA Neurology

24 September, 2021 16:51

Sleep duration associated with amyloid burden and cognitive decline

Journal

JAMA Neurology

22 September, 2021 22:56

Major surgery raises plasma biomarkers of brain injury, dementia risk

Journal

JAMA Neurology

22 September, 2021 16:32

Study questions screening for subclinical thyroid dysfunction to prevent cognitive decline

Journal

JAMA Internal Medicine

8 September, 2021 23:30

Number of people with dementia set to jump 40% to 78 mln by 2030 -WHO

2 September, 2021 15:24

Severe outcomes of COVID-19 in patients with dementia

Presented By

Dr Agathe Vrillon, Hôpital Lariboisière Fernand-Widal, France

Conference

EAN 2021

18 August, 2021 10:27

Promising diagnostic accuracy of plasma GFAP

Presented By

Dr Tandis Parvizi, Medical University of Vienna, Austria

Conference

EAN 2021

18 August, 2021 10:10

Sex modulates effect of cognitive reserve on subjective cognitive decline

Presented By

Dr Giulia Giacomucci, University of Florence, Italy

Conference

EAN 2021

18 August, 2021 10:05

Hypersensitivity to uncertainty in subjective cognitive decline

Presented By

Dr Bahaaeddin Attaallah, University of Oxford, United Kingdom

Conference

EAN 2021

18 August, 2021 10:00

Global young-onset dementia prevalence 119 per 100,000

Journal

JAMA Neurology

19 July, 2021 23:20

APOE-e4 allele tied to Alzheimer’s clinical and biomarker changes in Down syndrome

Journal

JAMA Neurology

14 July, 2021 23:20

Calculator validated for home-based dementia risk screening

Journal

Journal of Epidemiology and Community Health

8 July, 2021 22:37

Statins not tied to incident dementia or cognitive decline in older adults

Journal

Journal of the American College of Cardiology

29 June, 2021 23:51

Motor change patterns may suggest preclinical Alzheimer’s disease

Journal

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

29 June, 2021 23:33

Biogen working to speed up confirmatory study for approved Alzheimer’s drug

24 June, 2021 16:20

Lilly to seek accelerated FDA approval for Alzheimer’s drug this year

24 June, 2021 16:18

FDA documents show struggle over approval of new Alzheimer’s drug from Biogen

22 June, 2021 23:41

Rival treatments may help justify FDA gamble with Biogen Alzheimer’s drug

18 June, 2021 16:43

Obstructive sleep apnoea associated with lower cognition

Presented By

Dr David Colelli, University of Toronto, Canada

Conference

AAN 2021

16 June, 2021 11:49

NfL is a better marker for neurodegeneration than T-tau

Presented By

Mr Jordan Marks, Mayo Clinic, MN, USA

Conference

AAN 2021

16 June, 2021 11:49

Monoclonal antibody rapidly reduces brain amyloid

Presented By

Dr Chad Swanson, Neurology Business Group, Eisai Inc., NJ, USA

Conference

AAN 2021

16 June, 2021 11:44

Breast cancer treatment decreases risk of dementia

Conference

AAN 2021

16 June, 2021 11:43

Pimavanserin does not worsen motor function in patients with neurodegenerative disease

Trial

HARMONY, 019, 046, 032

Conference

AAN 2021

16 June, 2021 11:42

Lipophilic statins may raise risk of conversion from MCI to dementia

Conference

Society of Nuclear Medicine and Molecular Imaging 2021 annual meeting

15 June, 2021 15:40

Cholesterol catabolism, bile acid synthesis tied to dementia risk in men

Journal

PLoS Medicine

11 June, 2021 23:20

ANALYSIS-U.S. FDA faces mounting criticism over Alzheimer’s drug approval

11 June, 2021 15:32

Gene signature for plaque-eating microglia identified

Journal

Nature Communications

2 June, 2021 22:54

Biological definition of Alzheimer’s disease not suitable for clinical diagnosis

Journal

The Lancet Neurology

21 May, 2021 20:46

Memory decline in older adults similar with CABG and PCI

Journal

JAMA

18 May, 2021 23:08

Video exam may be effective alternative to in-person cognitive assessments

Journal

Journal of the American Geriatrics Society

14 May, 2021 23:22

Novel compound reverses Alzheimer’s disease in mice

Journal

Cell

7 May, 2021 22:13

New PET tracer detects early hallmark of Alzheimer’s disease

Journal

Molecular Psychiatry

6 May, 2021 22:03

Dense-core amyloid plaques may be protective, not destructive, in Alzheimer’s disease

Journal

Nature Immunology

3 May, 2021 22:40

Whole-genome sequencing reveals rare variants tied to Alzheimer’s disease

Journal

Alzheimer's and Dementia

15 April, 2021 23:21

More evidence that gum disease may play a role in Alzheimer’s disease

Journal

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

14 April, 2021 18:26

Adults with recent dementia diagnosis at increased risk for suicide

Journal

JAMA Psychiatry

5 April, 2021 22:03

Retinal changes may signal pre-clinical Alzheimer’s disease neuropathology

Journal

JAMA Ophthalmology

2 April, 2021 17:11

Sargramostim shows promise in Alzheimer’s disease

Journal

Alzheimer's and Dementia: Translational Research and Clinical Interventions

30 March, 2021 23:53

Retinal damage may signal risk for stroke and dementia

Conference

American Stroke Association International Stroke Conference 2021

25 March, 2021 16:01

Little consensus on referral to specialist palliative care for dementia patients

Journal

Journal of the American Geriatrics Society

19 March, 2021 20:56

Link between cardiovascular-risk management and dementia protection remains elusive

Journal

JAMA Neurology

10 March, 2021 15:43

Reverse BP dipping tied to dementia, Alzheimer’s disease in older men

Journal

Hypertension

19 February, 2021 23:37

Hyperglycemia tied to cognitive decline, vascular dementia

Journal

Diabetes, Obesity, and Metabolism

19 February, 2021 19:21

Visual reads of PET scans can help predict near-term clinical progression of dementia

Journal

JAMA Neurology

18 February, 2021 18:07

Benign prostatic hyperplasia tied to Alzheimer’s disease risk

Journal

EClinicalMedicine

16 February, 2021 23:06

Tau species in spinal fluid may track with brain tau, indicate stage of dementia

Journal

Brain

21 December, 2020 16:14

High risk of vascular dementia in patients with T2D

Presented By

Dr Carlos Celis-Morales, University of Glasgow, Scotland

Conference

EASD 2020

14 December, 2020 12:36

Study supports link between endosomal-traffic defect and Alzheimer’s

Journal

Science Translational Medicine

4 December, 2020 19:52

Neuroinflammation common in familial frontotemporal dementia

Journal

Journal of Neurology, Neurosurgery and Psychiatry

26 November, 2020 20:00

Retinal imaging may predict Alzheimer’s in those at genetic risk

Journal

JAMA Ophthalmology

20 November, 2020 17:11

Plasma P-tau217 emerging as biomarker of early AD

Journal

JAMA Neurology

11 November, 2020 18:18

Predicting MCI and dementia by assessing worrying about memory

Presented By

Prof. Frank Jessen, University Hospital of Cologne, Germany

Trial

Cohort study, AgeCoDe

Conference

ECNP 2020

2 November, 2020 16:49

Genomics of vascular dementia and stroke

Presented By

Prof. Elisabeth Tournier-Lasserve, Saint Louis Hospital, France

Conference

ECNP 2020

2 November, 2020 16:45

The PRISM project: focusing on biological parameters across neuropsychiatric disorders

Presented By

Dr Hugh Marston, Eli Lilly and Company Ltd, Germany

Conference

ECNP 2020

2 November, 2020 15:56

APOE-region variants linked to Alzheimer’s disease risk

Journal

JAMA Network Open

30 October, 2020 22:18

Unique Alzheimer’s disease risk loci found in African Americans

Journal

JAMA Neurology

23 October, 2020 20:20

Novel neuroimaging data have implications for recruitment for Alzheimer’s clinical trials

Journal

JAMA Neurology

21 October, 2020 16:48

Telemedicine could help rural patients with dementia

Journal

Maturitas

16 October, 2020 22:11

Sleep EEG-based brain-age index correlates with dementia

Journal

JAMA Network Open

8 October, 2020 18:23

French ‘Alzheimer’s village’: where nursing home meets the outside world

1 October, 2020 16:11

Non-Alzheimer’s disease pathophysiology in the elderly

Expert

Prof. Philip Scheltens, Amsterdam UMC, the Netherlands

Conference

EAN 2020

8 September, 2020 10:58

Novel genetic association with resistance to ERC tau deposition

Expert

Vijay K Ramanan, Mayo Clinic–Rochester, Minnesota, USA

Conference

EAN 2020

8 September, 2020 10:55

News on AD biomarkers

Conference

EAN 2020

8 September, 2020 10:50

Diastolic dysfunction novel risk factor for cognitive impairment

Expert

Dr A. Parker, Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, USA

Conference

EAN 2020

8 September, 2020 10:08

A necessary shift of focus to the earlier stages of Alzheimer’s

Presented By

Prof. Bart de Strooper, Katholieke Universiteit Leuven, Belgium

Conference

EAN 2019

27 August, 2019 23:51

Biomarkers and how to use them

Conference

EAN 2019

27 August, 2019 22:54

Antipsychotics increase mortality regardless of comorbidity

Presented By

Dr Ane Nørgaard, Rigshospitalet, Denmark

Conference

EAN 2019

27 August, 2019 21:55

PDD and DLB represent two different disorders

Conference

EAN 2019

27 August, 2019 14:57

Amyloid PET in cognitively impaired patients

Presented By

Prof. Gil Rabinovici, University of California San Francisco, USA

Trial

IDEAS

Conference

AAN 2019

30 July, 2019 23:14

Tight blood pressure control lowers risk of mild cognitive impairment

Presented By

Dr Jeff Williamson, Wake Forest Baptist Medical Center, Winston-Salem, USA

Trial

SPRINT MIND

Conference

AAN 2019

30 July, 2019 22:16

Two experimental antibodies reduce amyloid levels

Trial

Phase 3, PRIME, ENGAGE, EMERGE

Conference

AAN 2019

30 July, 2019 21:20

How to implement brain-healthy behaviour in clinical practice

Conference

AAN 2019

30 July, 2019 09:21