Home > Oncology > ASCO 2020 > Breast & Ovarian Cancer > Maintenance olaparib improves OS in relapsed ovarian cancer with BRCA1/2 mutation

Maintenance olaparib improves OS in relapsed ovarian cancer with BRCA1/2 mutation

Presented By
Prof. Andrés Poveda, Hospital Quironsalud, Spain

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Conference
ASCO 2020
Trial
Phase 3, SOLO2/ENGOT-ov21
Featured video: Final overall survival (OS) results from SOLO2/ENGOT-ov21: A phase III trial assessing maintenance olaparib in patients (pts) with platinum-sensitive, relapsed ovarian cancer and a BRCA mutation. https://vimeo.com/440627893 In patients with platinum-sensitive relapsed ovarian cancer harbouring BRCA1/2 mutation, final overall survival (OS) results from the phase 3 SOLO2/ENGOT-ov21 trial showed significant benefit for patients receiving maintenance treatment with olaparib over placebo. Prof. Andrés Poveda (Hospital Quironsalud, Spain) presented the results, after approximately 5 years of follow-up [1]. The trial enrolled patients with a BRCA mutation with relapsed high-grade serous ovarian cancer or endometrioid cancer. Patients had received at least 2 prior l...


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