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Distinguishing patients before AMI based on plaque morphology

Presented By
Dr Alfredo Ricchiuto, Università Cattolica del Sacro Cuore, Italy

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Conference
AHA 2021
Patients with and without pre-infarction angina (PIA) could be distinguished based on culprit plaque morphology imaged by intracoronary optical coherence tomography (OCT). Patients with PIA displayed higher rates of intact fibrous cap (IFC) and plaque healing, and lower rates of thrombus burden. These results provide insights into the association between plaque morphology and the clinical presentation of acute myocardial infarction (AMI). “It has been established that destabilisation in plaque morphology evolution is an important coronary thrombosis mechanism,” explained Dr Alfredo Ricchiuto (Università Cattolica del Sacro Cuore, Italy) [1]. “However, the association between culprit plaque morphology, healed culprit plaque prevalence, and the clinical presentation of AMI is mostly unexplored.” The current retrospective, observational study aimed to evaluate the differences in plaque morphology and healing capacity in patients with (n=50) and without PIA (n...


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