Home > Cardiology > AHA 2021 > Vascular Diseases: CAD > Early surgery outperforms conservative management in asymptomatic severe aortic stenosis

Early surgery outperforms conservative management in asymptomatic severe aortic stenosis

Presented By
Prof. Marko Banovic, University Clinical Centre of Serbia, Serbia

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Conference
AHA 2021
Trial
AVATAR
The AVATAR trial demonstrated benefits of early surgical aortic valve replacement compared with conservative management in patients with asymptomatic severe aortic stenosis with a normal left ventricular function. These results show that surgery is indicated when aortic stenosis is significant, albeit asymptomatic [1]. A recent randomised trial suggested that early surgery outperforms conservative management in a population of patients with very severe aortic stenosis [2]. However, surgery in asymptomatic patients with severe aortic stenosis remained a topic of debate. Thus, the prospective, multicentre, randomised, open-label AVATAR study (NCT02436655) assessed the efficacy and safety of early surgical valve replacement in a population of patients with asymptomatic severe aortic stenosis with a normal left ventricular function. Eligible patients underwent a mandat...


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