Home > Cardiology > AHA 2021 > Atrial Fibrillation > LAA ligation did not reduce recurrent atrial arrhythmias in persistent AF

LAA ligation did not reduce recurrent atrial arrhythmias in persistent AF

Presented By
Dr David Wilber, Loyola University Chicago, USA

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Conference
AHA 2021
Trial
aMAZE
Recurrent atrial arrhythmias were not reduced after adjunctive left atrial appendage (LAA) ligation compared with pulmonary vein antral isolation (PVAI) alone in patients with persistent atrial fibrillation (AF) undergoing AF ablation. Patients with early persistent AF and larger LA volumes may benefit more from adjunctive LAA ligation, exploratory analyses revealed. Future studies are needed to verify these exploratory outcomes. Dr David Wilber (Loyola University Chicago, IL, USA) explained that ablation outcomes via PVAI alone in patients with persistent AF are often suboptimal [1]. Therefore, secondary procedures such as LAA ligation are in development. The prospective, multicentre, randomised aMAZE trial (NCT02513797) aimed to assess the efficacy of LAA ligation with the LARIAT system compared with PVAI in decreasing recurrent atrial arrhythmias. Patients with ...


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