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Calcium supplements linked to harm in people with aortic stenosis

Journal
Heart
Reuters Health - 26/04/2022 - A large observational study suggests a need to rethink calcium supplements in people with aortic stenosis. The study of elderly patients with initially mild to moderate AS followed for more than five years found that supplemental calcium, with or without vitamin D, was associated with significantly lower survival and greater need for aortic-valve replacement (AVR). "Our findings suggest that supplemental calcium in this population does not confer any cardiovascular benefit, and instead these relationships should be thoughtfully considered in light of growing evidence and concern for CV harm particularly with unnecessary supplementation," write Dr. Samir Kapadia and colleagues with the Cleveland Clinic Ohio in the journal Heart. Their findings are based on 2,657 patients (mean age, 74 years; 42% women) with mild to moderate native AS. Nearly half (49%) were not taking any supplements, 12% took vitamin D alone and 39% took c...


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