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Conflicting periprocedural MI definitions impact clinical practice, research


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Journal
Journal of the American College of Cardiology
Reuters Health - 07/02/2022 - Among patients with chronic coronary syndrome (CCS), the presence and prognostic implications of periprocedural myocardial infarction (PPMI) vary tremendously, depending on which PPMI definition is utilized, researchers say. "How we assess PPMI is essential for three reasons," Dr. Lorenz Raber of the University of Bern in Switzerland told Reuters Health by email. "First, it impacts on patient care following revascularization procedures; second, it is considered as a quality measure; and third, it is used to compare different revascularization strategies (e.g., surgery vs. stent) in research." "We found that when applying the three widely accepted definitions, the frequency of PPMI numbers differed by a factor of 7... and the correlation with prognosis differed substantially," he said. "The use of a PPMI definition that inflates the number of PPMI substantially without prognostic impact - i.e., the 4th Universal Definition of Myoc...


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