Home > Cardiology > EHRA 2022 > Developments in Devices > Conduction system pacing potential alternative for biventricular pacing in heart failure

Conduction system pacing potential alternative for biventricular pacing in heart failure

Presented By
Dr Margarida Pujol-López, Institut Clínic Cardiovascular, Spain
Presented by
Margarida Pujol-López Institut Clínic Cardiovascular
Conference
EHRA 2022
Trial
LEVEL-AT
Doi
https://doi.org/10.55788/09658bd5
Conduction system pacing (CSP) demonstrated non-inferiority to biventricular pacing (BiVP) in terms of cardiac resynchronisation and ventricular remodelling in patients with heart failure and wide QRS segments. Evidence from the randomised-controlled LEVEL-AT trial suggests that CSP may be an alternative to BiVP in these patients, but additional studies are warranted before changing guidelines. CSP is an emerging technique to treat patients with an indication for cardiac resynchronisation therapy (CRT), but only a few randomised studies have compared the BiVP therapy with CSP. Dr Margarida Pujol-López (Institut Clínic Cardiovascular, Spain) and colleagues designed the non-inferiority LEVEL-AT trial (NCT04054895), in which patients with heart failure (a left ventricular ejection fracture ≤35%) and a wide QRS segment (≥130 ms in left bundle branch block/≥15...


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