Home > Cardiology > EHRA 2022 > Updates on Ablation > Real-world safety results on pulsed-field ablation with pentaspline catheter

Real-world safety results on pulsed-field ablation with pentaspline catheter

Presented By
Dr Vivek Reddy, Mount Sinai Hospital, NY, USA
Presented by
Vivek Reddy Mount Sinai Hospital
Conference
EHRA 2022
Trial
MANIFEST-PF
Doi
https://doi.org/10.55788/2bfa9dbd
The MANIFEST-PF survey demonstrated that pulsed-field ablation (PFA) with the pentaspline catheter achieved pulmonary vein isolation (PVI) in 99.9% of the investigated real-world cases. The safety profile of this technique was reassuring with regard to oesophageal damage and consistent with that of preferential tissue ablation. PFA has shown to be safe and efficacious in first-in-human trials, but the sample sizes of these trials were rather limited [1,2]. In the current retrospective study, Dr Vivek Reddy (Mount Sinai Hospital, NY, USA) and colleagues aimed to assess the real-world performance of the pentaspline PFA catheter [3]. More specifically, the objectives were to assess the safety, effectiveness, and usage of this tool in clinical practice. A survey was sent to 24 centres to gather data from 90 operators on 1,758 patients who underwent PFA. An indication of paroxysmal atrial fibrillation (AF) was detected in 57.5% of the patients ...


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