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Guidelines adherence reduces bleeding risk after surgery and childbirth for VWD patients

Presented By
Dr Brian Craven, Royal Free London NHS Foundation Trust, United Kingdom

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Conference
ISTH 2020
  A retrospective, single-centre cohort study following 30 patients with Von Willebrand Disease (VWD) who underwent major surgery or childbirth revealed that adherence to current guidelines can reduce the risk of major bleeding events to an acceptable range [1]. Patients with VWD, the most common heritable bleeding disorder, are at increased bleeding risk from invasive procedures. To prevent complications, prophylactic treatment is often administered and recommended in current guidelines. For patients undergoing major surgery, several factor replacement options exist. The current study assessed how closely real-world practice in large centres is aligned with national guidelines and how the recommendations influence post-operative bleeding and/or thrombosis. The analysis included 30 VWD patients who underwent major surgery or childbirth (both vaginal delivery or caesarean section) and received factor replacement. Patients were eligible to...


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