Home > Cardiology > Stroke-related brain death in young heart donors tied to higher recipient mortality

Stroke-related brain death in young heart donors tied to higher recipient mortality


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Journal
Journal of the American College of Cardiology
Reuters Health - 14/03/2022 - Stroke as a cause of death in young organ donors is linked with worse survival for heart transplant recipients, U.S. data show. The same is not true when stroke was the cause of death for older donors, however, according to Dr. Takahisa Mikami of Tufts University School of Medicine in Boston and colleagues. The researchers analyzed data from the United Network for Organ Sharing on 18,438 patients who received new hearts between 2005 and 2018, including 3,761 whose donors died of stroke. Overall, they saw no difference in mortality risk between heart recipients whose donors did or did not die of stroke (adjusted HR,1.07,95% CI 0.096-1.19), according to a report in the Journal of the American College of Cardiology. But when heart donors were age 40 or younger, stroke-related death was associated with higher five-year mortality (hazard ratio, 1.17; 95% CI: 1.02-1.35) and higher risk of graft failure during follow-up (HR, 1.30...


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