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TAVR may improve neurocognitive function in some patients


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Journal
JACC: Cardiovascular Interventions
Reuters Health - 20/11/2020 - Patients with baseline Mini-Mental Status Examination (MMSE) scores in the low-normal range, or lower, experienced greater neurocognitive improvement after transcatheter aortic valve replacement (TAVR) than after surgical aortic valve replacement (SAVR) in a small, post-hoc analysis. "Our study and other smaller studies suggest there could be improvement in neurocognitive function after TAVR in some patients with abnormal baseline cognition," Dr. Srinivasa Potluri of Baylor Scott and White The Heart Hospital-Plano in Texas told Reuters Health by email. "Therefore, patients with lower MMSE (dementia) at baseline could be considered for TAVR after heart-team discussion weighing benefits and risks." That said, he added, "Our findings are hypothesis-generating and need to be confirmed in larger studies." The team's post hoc analysis of the multicenter PARTNER 3 trial (


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