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For sentinel node-positive melanoma treatment, location matters


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Journal
Annals of Surgery
Reuters Health - 21/02/2022 - Similar-risk melanoma patients with positive sentinel nodes are managed with nodal observation alone, nodal observation with adjuvant systemic therapy, or completion lymph node dissection (CLND) and adjuvant systemic therapy depending at least in part on the location of their treatment center, an international analysis found. While most patients now receive nodal surveillance instead of CLND, and adjuvant systemic therapy use is increasing, significant geographic and center-level variation remains which merits further study, Dr. Kristy Broman of the University of Alabama at Birmingham and colleagues note in Annals of Surgery. "We have good evidence to support a more minimal surgical approach for most patients with microscopic cancer in their lymph nodes, sparing patients additional surgery and long-term complications," Dr. Broman said. "This study shows that, unlike the pace of adoption that we see for many scientific innovations, these...


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