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High-fiber diet tied to better immunotherapy response and progression-free survival in melanoma


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Journal
Science
Reuters Health - 03/01/2022 - Patients with melanoma who ate more fiber-rich foods when starting immunotherapy responded better to therapy and had improved progression-free survival compared to those who did not get enough dietary fiber, researchers say. Further, taking commercial probiotic supplements did not help treatment outcomes. "Though we were not surprised (by) the findings that increased dietary fiber intake was associated with better outcomes, the strength and magnitude of this association was somewhat surprising to us," Dr. Jennifer Wargo of the University of Texas MD Anderson Cancer Center in Houston told Reuters Health by email. "In addition, the low proportion of patients reporting 'sufficient' dietary fiber (29%) was eye-opening." "The findings regarding use of commercially available probiotics were quite surprising (31% of our patients)," she said. "Importantly, when we considered dietary fiber and probiotic use together, we found that patient...


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