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International consensus reached on methotrexate dosing for psoriasis


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Journal
JAMA Dermatology
Reuters Health - 07/04/2022 - Dermatologists worldwide reached consensus on 20 of 21 proposals involving methotrexate (MTX) dosing in patients with psoriasis, with the intent of harmonizing treatment across global psoriasis patient populations. "The variability in treatment regimens might contribute to suboptimal treatment with MTX or can lead to early discontinuation of treatment due to limited efficacy or side effects," Dr. Astrid van Huizen of the University of Amsterdam told Reuters Health by email. "With the publication of this consensus study, we hope to raise awareness on the different MTX dosages used in daily practice and the need for a more uniform dosing regimen." "We discussed many aspects of MTX dosing in this consensus study," she added, "including test dose, start dose, the increase or decrease of the dose, administration form, maximum dose, administration and the use of folic acid specified for specific populations - adults, children and vulnerable p...


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