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Superficial radiotherapy tied to remission, better quality of life in severe Hailey-Hailey disease


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Journal
JAMA Dermatology
Reuters Health - 28/01/2022 - In patients with severe, treatment-resistant Hailey-Hailey disease (HHD), a rare skin disorder, superficial radiotherapy is associated with successful remission and improvements in health-related quality of life (QoL), according to a new study. "The study results suggest that superficial radiotherapy may be associated with remission in the treatment of Hailey-Hailey disease and potentially provides a long-term improvement of treated skin areas," Dr. Stine Regin Wiegell of the University of Copenhagen, Denmark, and colleagues write in JAMA Dermatology. Painful erosions of the skin in sensitive areas, such as the groin and genitals, are a key manifestation of HHD, and "the disease has a great negative impact of the patient's QoL and decreases work ability and sex life," Dr. Wiegell explained in an email to Reuters Health. Standard treatments for HHD, such as antibiotics, are frequently used to control flares, but do not induce long...


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