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Improvement in hepatic steatosis but worse lipid profile after alcohol cessation

Presented By
Dr Eliot Alexander Rapoport, University of Illinois at Peoria, IL, USA
Presented by
Eliot Alexander Rapoport University of Illinois at Peoria
Conference
DDW 2022
Doi
https://doi.org/10.55788/1655ac74
A study conducted among patients with alcohol use disorder enrolled in an alcohol detoxification programme showed that hepatic steatosis improved rapidly after drinking was stopped. Unfortunately, this was accompanied by a significant change from an athero-protective profile (high HDL, low LDL) to an atherogenic one. The study, including 93 patients, categorised lipoprotein (LP) changes and the association between LP-Insulin Resistance Index (LP-IR) and hepatic steatosis following alcohol detoxification [1]. Patients that were enrolled in a 4-week alcohol detoxification programme at the National Institute of Health and with the last drink within 3 days of admission were registered. Laboratory values and NMR LipoProfile Testing® were collected upon admission and during the first and third weeks. Fibroscan® with controlled attenuation parameter (CAP) was performed during the first, second, and fourth week. The Area Under Receiver Operator Characteris...


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