Home > Gastroenterology > DDW 2022 > Other Highlighted Research > Normal BMI in NAFLD patients is associated with a higher risk of cardiovascular disease

Normal BMI in NAFLD patients is associated with a higher risk of cardiovascular disease

Presented By
Dr Karn Wijarnpreecha, University of Michigan, MI, USA
Presented by
Karn Wijarnpreecha University of Michigan
Conference
DDW 2022
Doi
https://doi.org/10.55788/fb6a2249
A retrospective cohort study including more than 10,000 adults with non-alcoholic fatty liver disease (NAFLD) showed that, surprisingly, lean people with NAFLD have a higher risk of cardiovascular disease than those who are overweight or obese. This held true despite lean patients having a lower prevalence of risk factors like hypertension and dyslipidaemia. “It seems counterintuitive that those with a normal BMI would have a higher prevalence of cardiovascular disease (CVD), but our research highlighted this connection,” said lead study author Dr Karn Wijarnpreecha (University of Michigan, MI, USA). “This finding could have significant implications on patient care and warrants further analysis.” Although most NAFLD patients are overweight or obese, approximately 10–20% have a normal BMI. The retrospective cohort study looked at 18,793 adults with NAFLD at the University of Michigan from 2012 to 2021. Patients were categorised into lean (BMI 18.5–24...


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