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What’s the best treatment modality for resectable stomach cancer?


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Journal
JAMA Network Open
Reuters Health - 28/12/2021 - For resectable gastric cancer, neoadjuvant chemoradiation may be better than other treatment modalities for achieving pathologic complete response (pCR) and treatment with any chemotherapy may provide the biggest survival benefit, according to a new analysis. "Treatment of resectable gastric cancer uses a multimodal approach, including surgical treatment and chemotherapy with or without radiation therapy, and the optimal treatment strategy and timing of each of these modalities is unknown," researchers note in JAMA Network Open. To investigate, Dr. Jun Gong with Cedars-Sinai Medical Center, in Los Angeles, and colleagues used the National Cancer Database to do a comparative effectiveness analysis of various neoadjuvant and adjuvant treatment modalities in more than 3,000 patients with resectable gastric cancer. They created nine treatment groups: neoadjuvant chemoradiation (nCRT) only, neoadjuvant chemotherapy only, adjuvant chem...


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