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Mother and baby fine after first reported use of immune-checkpoint inhibitor during pregnancy


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Journal
American Journal of Hematology
Reuters Health -  18/04/2022 - A woman who suffered a relapse of classic Hodgkin lymphoma while pregnant was successfully treated with the immune-checkpoint inhibitor nivolumab, in what is believed to be the first reported case in the literature. "Long story short, the patient did amazing. She carried the pregnancy to term and delivered spontaneously at 38 weeks," said Dr. Andrew M. Evens of Rutgers Cancer Institute of New Jersey and Robert Wood Johnson University Hospital, in New Brunswick. "She had a bone-marrow transplant about three months after delivery. Now almost a year later, both mother and baby are doing fantastic," he told Reuters Health by phone. Dr. Evens and colleagues describe the case in the American Journal of Hematology. "There have been reports in the medical literature of the use of immune checkpoint inhibitors for patients with cancer with unexpected pregnancy, including patients who were on clinical trials when pregnancy was disco...


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