Home > Cardiology > Once-daily triple combination pill may best usual care for high blood pressure

Once-daily triple combination pill may best usual care for high blood pressure


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Journal
JAMA Cardiology
Reuters Health - 19/04/2022 -In patients with mild-to-moderate hypertension, a low-dose triple combination pill was associated with longer time at target blood pressure (BP) compared with usual care in a secondary analysis of the TRIUMPH study. TRIUMPH (Triple Pill vs Usual Care Management for Patients With Mild-to-Moderate Hypertension) was an open-label randomized clinical trial of low-dose triple BP therapy versus usual care conducted in urban hospital clinics in Sri Lanka. Participants were randomized to once-daily fixed-dose triple combination pill (telmisartan 20 mg, amlodipine 2.5 mg, and chlorthalidone 12.5 mg) therapy versus usual care, and followed for 24 weeks. "To date, BP guidelines and clinical practice have only focused on BP targets based on one-off measurements at a single time point, without consideration of the proportion of time that people are at target BP," Dr. Sonali Gnanenthiran of the University of New South Wales in Australia told Re...


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