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Study supports citrate over heparin anticoagulation for continuous dialysis


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Journal
JAMA
Reuters Health - 26/10/2020 - A large randomized controlled trial supports the use of regional citrate over heparin anticoagulation to help prevent blood clot formation at the filter in patients receiving continuous dialysis therapies. Dialysis filter life was 15 hours longer in the regional citrate anticoagulation group compared to the heparin group, Dr. Alexander Zarbock reported October 23 during the "high-impact" clinical trials session at the Kidney Week 2020 virtual annual meeting. The study was simultaneously published in JAMA. Blood clot formation at the filter is a common complication in patients receiving continuous dialysis therapies. Systemic use of heparin and regional citrate are the two main anticoagulant strategies. Current guidelines recommend the use of citrate over heparin, but the evidence level is considered low. Dr. Zarbock, from University Hospital Munster in Germany, and colleagues conducted the RICH trial to test whether regional citr...


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