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Migraine may be an important obstetric risk factor

Presented By
Dr Alexandra Purdue-Smithe, Harvard Medical School, MA, USA
Presented by
Alexandra Purdue-Smithe Harvard Medical School
AAN 2022
In a large study evaluating over 30,000 pregnancies between 1989 and 2009, pre-pregnancy migraine had a higher risk of pre-term delivery, gestational hypertension, and pre-eclampsia. Migraine history and phenotype may be important considerations in obstetric risk assessment and management. Migraine and adverse pregnancy outcomes share a common pathophysiology [1]. “Roughly 20% of women of childbearing age experience migraine, but the impact of migraine on pregnancy outcomes has not been well understood,” said study author Dr Alexandra Purdue-Smithe (Harvard Medical School, MA, USA) [2]. This is due to a lack of large prospective studies. Her group in Boston used data from 30,555 pregnancies in 19,694 participants of the longitudinal Nurses’ Health Study 2 and estimated associations of confirmed migraine before pregnancy with pre-term delivery (<37 weeks), gestational diabetes mellitus (GDM), gestational hypertension, pre-eclampsia, and low bir...

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