Home > Neurology > Autism risk genes take different paths but converge on the same brain cell types

Autism risk genes take different paths but converge on the same brain cell types


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Journal
Nature
Reuters Health - 14/02/2022 - Three autism spectrum disorder (ASD) risk genes affect similar aspects of development and the same types of neurons, but they act through different molecular mechanisms, preclinical research suggests.  The findings lay the groundwork for identifying new diagnostics and exploring potential treatments, according to Dr. Paola Arlotta of Harvard University in Cambridge and colleagues.  "When we saw that, one after the other, each of these genes affected the same cell types and a similar developmental process, we (had) a eureka moment!" Dr. Arlotta told Reuters Health by email.


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