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Certain antihypertensive meds might help prevent cognitive decline


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Journal
JAMA Network Open
Reuters Health - 11/02/2022 - Antihypertensive medications that stimulate type-2 and -4 angiotensin II receptors are associated with lower rates of cognitive impairment or probable dementia compared with drugs that inhibit these receptors, according to new research.  A secondary analysis of data from the SPRINT trial revealed that use of stimulating versus inhibiting antihypertensives was associated with 26% lower risk of amnestic mild cognitive impairment (MCI) and a non-significantly lower risk of probable dementia, researchers report in JAMA Network Open.  "Residual confounding cannot be ruled out. If these results are replicated in randomized clinical trial...


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