Home > Neurology > Combining antidepressants tied to better outcomes than monotherapy

Combining antidepressants tied to better outcomes than monotherapy


Notice: Undefined index: new_doi_fields in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 138

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 138

Notice: Undefined index: new_doi_fields in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 174

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 174

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 175
Journal
JAMA Psychiatry
Reuters Health - 24/02/2022 - Combination antidepressant therapy, particularly with an antagonist of presynaptic alph2-autoreceptors, may be an effective option for patients who don't respond to monotherapy and a possible first-line treatment for severe depression, researchers suggest.  "Antidepressant combination therapy has been implemented as a possible second-step treatment in practice guidelines; however, in light of the solid evidence for specific combinations that our findings provide, we believe these should be favored over other second-step treatments that are less evidence-based, such as switching an antidepressant or increasing the dose," Dr. Christopher Baethge of the University of Cologne and Dr. Jonathan Henssler of Charite University Medicine in Berlin told Reuters Health in a joint email.


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on