Home > Neurology > Magnesium and hydrogen may be neuroprotective in subarachnoid hemorrhage

Magnesium and hydrogen may be neuroprotective in subarachnoid hemorrhage


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Journal
Stroke
Reuters Health - 08/01/2021 - A small clinical trial from Japan suggests a role for magnesium alone or with hydrogen in improving outcomes of patients with poor-grade subarachnoid hemorrhage (SAH). The study found that intracisternal magnesium sulfate infusion started right after surgery reduced the incidence of cerebral vasospasm and delayed cerebral ischemia and improved clinical outcomes without complications. Combining intracisternal magnesium infusion with intravenous hydrogen had additive benefits. Dr. Satoru Takeuchi and colleagues with the National Defense Medical College in Saitama report their findings in the journal Stroke. While many questions remain, these results are "encouraging . . . and demonstrate a real possibility of neuroprotection for intracisternal infusion of magnesium and with a promising additional effect of intravenous hydrogen," write editorialists Dr. Colum Amory and Dr. Panayiotis Varelas of Albany Medical Center in New York....


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