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What’s the best brain-injury biomarker after cardiac arrest?


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Journal
JAMA Neurology
Reuters Health - 03/03/2022 - When it comes to blood-based brain injury biomarkers, neurofilament light (Nf-L) chain showed the highest accuracy in predicting unfavorable neurologic outcome in patients with a hypoxic ischemic brain injury after cardiac arrest in a meta-analytic review.  "Brain injury biomarkers released into circulation from the injured neurovascular unit are important prognostic tools in patients with cardiac arrest who develop hypoxic ischemic brain injury (HIBI) after return of spontaneous circulation (ROSC)," the authors note in JAMA Neurology.  Dr. Mypinder S. Sekhorn of Vancouver General Hospital, in Canada, and colleagues pooled data fro...


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