Home > Gastroenterology > Modest activity of atezolizumab plus bevacizumab in Child-Pugh B HCC

Modest activity of atezolizumab plus bevacizumab in Child-Pugh B HCC

Presented By
Dr Hyeyeong Kim, Ulsan University Hospital, South Korea

Notice: Undefined index: new_doi_fields in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 138

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 138

Notice: Undefined index: new_doi_fields in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 174

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 174

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/functions.php on line 175
Conference
ASCO GI 2022
Trial
Phase 3, IMbrave150
The combination of atezolizumab plus bevacizumab demonstrated modest clinical activity in patients with Child-Pugh B advanced hepatocellular carcinoma (HCC) in the phase 3 IMbrave150 trial. However, the frequency of serious adverse events (AEs) was relatively high. Further studies are needed to carefully select the patients who may benefit from this combination regimen [1]. “The phase 3 IMbrave150 trial (NCT03434379) showed encouraging efficacy and safety of atezolizumab plus bevacizumab as first-line therapy in patients with advanced HCC,” said Dr Hyeyeong Kim (Ulsan University Hospital, South Korea). “However, this trial did not include patients with Child-Pugh B HCC. Therefore, a retrospective study was performed to assess 37 Child-Pugh B classified patients with advanced HCC who underwent atezolizumab plus bevacizumab therapy in the first-line.” The data wa...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on