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Benign adrenal tumors often overproduce cortisol, may raise hypertension, diabetes risks


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Journal
Annals of Internal Medicine
Reuters Health - 03/01/2022 - Mild autonomous cortisol secretion (MACS) occurred in nearly half of patients, mainly women, with benign adrenal tumors, and was associated with higher prevalence of hypertension and type 2 diabetes in a cross-sectional study. "Adrenal tumors affect 3-5% of the population and are mostly detected incidentally," Dr. Wiebke Arlt of the University of Birmingham told Reuters Health by email. "Radiologists often don't mention the adrenal nodule in their reports, and if they (do), in many patients this does not prompt a referral to an endocrinologist." "However, nearly half of the people with benign adrenal tumors we investigated showed evidence of cortisol overproduction, which was a surprising finding," she said. "We also found that increasing cortisol excess comes with an increasing risk of developing type 2 diabetes and high blood pressure." "Another surprising finding was that the majority of affected individuals were women and wit...


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