Home > Oncology > ELCC 2022 > Small Cell Lung Cancer > Radiation dose on oesophagus predicts OS in SCLC patients treated with chemoradiotherapy

Radiation dose on oesophagus predicts OS in SCLC patients treated with chemoradiotherapy

Presented By
Dr Bilal Tahir, University of Sheffield, United Kingdom
Presented by
Bilal Tahir University of Sheffield, United Kingdom
Conference
ELCC 2022
Doi
https://doi.org/10.55788/38c2928d
In patients with small cell lung cancer (SCLC) who undergo chemoradiotherapy (CRT), radiation dose on the oesophagus predicted overall survival (OS) in a retrospective study. CRT is a standard treatment for most patients with limited-stage SCLC. Recent data in NSCLC suggested that heart dose independently predicts OS after radical CRT [1]. To date, however, limited research has been reported on the impact of heart dose on OS of SCLC patients [2]. Further investigation is needed to determine the predictive value of heart dose and doses to other structures local to the tumour, such as the lungs or oesophagus. Investigators reviewed the records of 184 SCLC patients treated with radical CRT to determine the impact of heart, lung, and oesophageal dosimetry on the OS. The median age of investigated patients was 65 years; 87.5% of patients were diagnosed with limited-stage SCLC, 9.2% had extensive-stage SCLC. Multiple whole-heart dose-volume histogram (DV...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on