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Positive lymph nodes not a reliable indicator for chemo in some women with breast cancer


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Conference
American Society of Breast Surgeons annual meeting
Reuters Health - 12/04/2022 - Sentinel node biopsy may not be helpful for adjuvant chemotherapy decisions in some older women with breast cancer, according to featured research presented at the American Society of Breast Surgeons annual meeting. "Sentinel node biopsy has some associated morbidity and is an additional procedure in the operating room. However, it may not provide the necessary information for decision-making about adjuvant chemotherapy," lead investigator Katharine Yao with University of Chicago said in a news release. "For this patient population, consideration of other tumor factors including possibly an Oncotype score may be more useful than nodal status," Dr. Yao added. Dr. Yao and colleagues assessed the correlation between nodal status and the Oncotype Dx 21-gene recurrence score, which reflects a tumor's individual biology and is widely used to aid decisions about adjuvant chemotherapy. Using the National Cancer Database, they anal...


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