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Women experience more, and more severe, toxicities from many types of cancer treatment


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Journal
Journal of Clinical Oncology
Reuters Health - 22/02/2022 - Across cancer treatment modalities, women experience more severe symptomatic and hematologic adverse events (AEs) than men, especially from immunotherapy, a retrospective analysis found. "Prior studies had shown that there were notable sex differences in toxicity from chemotherapy treatments. But almost no research has examined whether these differences were still evident for newer, modern treatments," Dr. Joseph Unger of the Fred Hutchinson Cancer Research Center in Seattle told Reuters Health by email. "We found that sex differences in toxicity persisted for the newer treatments too, especially for immune therapies, with women having a nearly 50% increased risk of severe toxicity compared to men." "If confirmed by others," he said, "these findings would indicate that the sex of patients with cancer would be one variable to consider when assessing treatment risks." As reported in the Journal of Clinical Oncology, Dr. Unger and c...


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