Home > Pulmonology > Obesity may hinder response to immunotherapy for allergies, asthma, mouse study suggests

Obesity may hinder response to immunotherapy for allergies, asthma, mouse study suggests


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Journal
Nature
Reuters Health - 06/04/2022 -  Obesity altered the immune system response to immunotherapy for allergies and asthma in a mouse study.  "The most critical next steps would to explore the therapeutic approach in non-human primates, where the immune response is stronger and similar to humans," Dr. Ronald Evans of The Salk Institute for Biological Studies in La Jolla told Reuters Health by email. "Secondly, to explore patients who take peroxisome proliferator-activated receptor-gamma (PPARg) therapy to see if there is a lower incidence for atopic dermatitis (AD)."  "While PPARg drugs are approved for diabetes, they have long-ter side effects, such as weight gain an...


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