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Laboratory and clinical signs 24h after hospitalisation predict MIS-C in children

Presented By
Dr Matthew Clark, Vanderbilt University Medical Center, TN, USA

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Conference
ACR 2021
Hypotension, abdominal pain, rash, and serum sodium concentration in children in the first 24 hours after hospital admission were indicators of COVID-19-associated multisystem inflammatory syndrome (MIS-C), according to a retrospective chart review analysis. Identifying affected children early is key to the successful management of this dangerous syndrome. MIS-C is a new syndrome associated with SARS-CoV-2 infection that has been increasingly reported in children. Patients with MIS-C usually present with persistent fever, abdominal pain, vomiting, diarrhoea, skin rash, and mucocutaneous lesions. MIS-C associated with COVID-19 may rapidly progress to hypotension and shock with cardiac and other end-organ injuries. “Clinically, we often found it difficult to separate MIS-C from other common childhood illnesses. To solve this problem, we set out to identify features that are distinctive of our patients with MIS-C and to use those for a prediction model,” said...


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