Home > Oncology > Blacks in clinical trials respond better than whites to radiation for localized prostate cancer

Blacks in clinical trials respond better than whites to radiation for localized prostate cancer


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Journal
JAMA Network Open
Reuters Health - 11/01/2022 - Among men with localized prostate cancer enrolled in clinical trials, Blacks had more aggressive disease but also better treatment outcomes than whites, a meta-analysis shows. "We were surprised to see how robust the results were - improved outcomes across the board, even for early disease endpoints like biochemical recurrence," Dr. Amar Kishan of the University of California, Los Angeles told Reuters Health by email. "Prior lines of evidence had hinted at the differences favoring Black men in terms of prostate cancer-specific mortality and survival in advanced disease, but here we are looking at very early endpoints as well." As reported in JAMA Network Open, Dr. Kishan and colleagues searched the literature for randomized controlled trials of Blacks and whites receiving radiation therapy for localized prostate cancer conducted by the NRG Oncology/Radiation Therapy Oncology Group from 1990 - 2010. The main outcomes were subdistr...


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