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Mayo classification by ultrasound useful in predicting rapid progression of rare kidney disease


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Journal
Clinical Kidney Journal
Reuters Health - 10/01/2022 - The Mayo classification (MC) of autosomal dominant polycystic kidney disease (ADPKD) based on ultrasound rather than magnetic resonance imaging (MRI) findings performs well, especially at the extremes of the MC (classes 1A, 1D, and 1E), and could be an option in hospitals with limited access to MRI, report clinicians from Spain. ADPKD is the most common cause of inherited kidney disease and shows a broad phenotypic spectrum. Identifying patients at high risk for rapid progression has become increasingly important given the availability of new treatments, such as tolvaptan, recently approved for rapidly progressing ADPKD. There are several tools to help predict disease progression in ADPKD, but no consensus on the optimal prediction model for the identification of rapid progression, note Dr. Javier Naranjo of Puerta del Mar University Hospital, in Cadiz, and colleagues in the Clinical Kidney Journal. They assessed the performance ...


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