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Pregnancy outcomes improving after treatment for high-grade cervical neoplasia


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Journal
Annals of Internal Medicine
Reuters Health - 07/02/2022 - The risk for pregnancy-related complications following treatment for grade-3 cervical intraepithelial neoplasia (CIN 3) has declined over time, thanks to advances in treatment, a new study indicates. However, women treated for CIN 3 should still be managed as "high risk" to reduce risk of preterm birth, infant sepsis, and other adverse outcomes, researchers write in Annals of Internal Medicine. Treatment for CIN 3 removes or destroys part of the cervix and might subsequently influence pregnancy outcomes. However, over the years, treatment for CIN 3 has advanced, with more conservative treatment methods used today. The researchers used data from five national Swedish registries to investigate pregnancy outcomes in women diagnosed with CIN 3 between 1973 and 2018. They identified 78,450 births after a maternal CIN 3 diagnosis and matched them to 784,500 births to women without a CIN 3 diagnosis. Even after accounting for fam...


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