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Shorter IV antibiotic courses likely effective for many urinary tract infections in infants


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Journal
Pediatrics
Reuters Health - 09/02/2022 - Shorter intravenous (IV) antibiotic courses, with an early switch to oral antibiotics, can be considered for infants ages 90 days or less with bacteremic or nonbacteremic urinary tract infection (UTI), a systematic review suggests. "We found that for bacteremic UTI, seven days or less of IV treatment is appropriate, while for nonbacteremic UTI, three days or less would be sufficient," Dr. Amanda Gwee of the University of Melbourne, Victoria told Reuters Health by email. "These shorter IV courses were not associated with an increased risk of getting a further UTI, requiring hospitalization, or needing admission to an intensive care unit." Importantly, she added, "These findings only apply to babies who are not septic and those in whom meningitis has been excluded." "For babies aged between 30 and 90 days, three studies reported good outcomes with oral antibiotic treatment alone," she noted. "But these studies only included 85 babi...


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