Tag: Pembrolizumab

Adding lenvatinib to pembrolizumab does not improve survival in advanced urothelial carcinoma
Sacituzumab govitecan effective in platinum-refractory metastatic urothelial cancer

DFS benefits with adjuvant pembrolizumab in RCC persist with longer follow-up
Updates on pembrolizumab for oesophageal and gastric cancer
Pembrolizumab safe and efficacious in advanced hepatocellular carcinoma



Neoadjuvant pembrolizumab plus chemotherapy benefits event-free survival in TNBC

Pembrolizumab plus chemotherapy benefits patients with combined positive score ≥10

Double-positive results for triple-negative metastatic breast cancer
TCR clonality predicts pembrolizumab response in NSCLC
Adjuvant immunotherapy reduces risk of disease recurrence in stage II melanoma

Combining T-VEC and pembrolizumab does not significantly improve survival in advanced, unresectable melanoma
Pembrolizumab prolongs survival in persistent, recurrent, or metastatic cervical cancer
Pembrolizumab has durable effect in previously treated MSI-H/dMMR advanced endometrial cancer
Pembrolizumab shows potential in TKI-resistant EGFR+ NSCLC, not ALK+

KEYNOTE-564: First positive phase 3 results with adjuvant checkpoint inhibition in RCC
Pembrolizumab benefits survival in MSI-H/dMMR metastastic colorectal cancer

Post-nephrectomy pembrolizumab improves disease-free survival
Promising efficacy and safety of feladilimab in recurrent/metastatic urothelial carcinoma
Immuno-oncology agents are effective in treating classic Hodgkin’s lymphoma

CLEAR trial: promising new combination to treat RCC

Chemoimmunotherapy is effective in a subset of small cell lung cancer patients
Lenvatinib plus pembrolizumab prolongs survival in renal cell carcinoma
First-line pembrolizumab shows superior PFS in MSI-H/dMMR mCRC
Neoadjuvant pembrolizumab in locally-advanced rectal cancer: primary results
Second-line pembrolizumab after progression on sorafenib benefits OS/PFS in advanced HCC
Phase 2 study supports first-line pembrolizumab in advanced HCC

Pembrolizumab as first-line in MSI-H mCRC
Pembrolizumab improves PFS for relapsed/refractory Hodgkin lymphoma
ES-SCLC: pembrolizumab KEYNOTE-604 data
Combination pembrolizumab/chemo improves PFS in metastatic TNBC
Adjuvant pembrolizumab: durable RFS for stage III melanoma
Pembrolizumab plus low-dose ipilimumab well tolerated after progression on PD1 antibody therapy
Understanding MIBC biology for novel treatment options
KEYNOTE-426: no QoL differences pembrolizumab + axitinib versus sunitinib
Pembrolizumab leads to higher toxicity risk in obese melanoma patients

Neoadjuvant + adjuvant pembrolizumab improves pCR in triple-negative breast cancer with lymph node involvement
Triple negative breast cancer gets positive news: KEYNOTE-522 interim results
Improved response rates without survival benefit with pembrolizumab in pretreated mesothelioma
Enfortumab vedotin and pembrolizumab in advanced bladder cancer: initial results

First-line pembrolizumab monotherapy offers durable OS benefit vs chemotherapy in NSCLC patients with high PD-L1 expression
Pembrolizumab + chemotherapy beneficial in advanced NSCLC, even without PD-L1 expression
KEYNOTE-062: Pembrolizumab combination fails to improve survival in gastric/GEJ cancer
Overcoming the challenges of immunotherapy in non–small cell lung cancer
Pembrolizumab monotherapy leads to 5-year survival in some patients with NSCLC

I-O monotherapy
Combo I-O plus chemotherapy
Immunotherapy in SCLC: trial data

Updated interim results of phase 2 trial of pembrolizumab for high-risk NMIBC unresponsive to BCG
Combination therapies: Where are we in 2018?
