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Comorbidity in adult psoriasis

comorbidity in adult psoriasis Psoriasis was once thought to only involve the skin, but today the disease is recognised as a chronic systemic disease associated with a high burden of comorbidities.1 Psoriatic arthritis is the most well-known comorbidity, which is considered as a disease entity with psoriasis, affecting ∼20% of the patients.2 There is an extensive list of other disorders…

SARS-CoV-2 vaccination management in patients with chronic plaque psoriasis

IntroductionIn December 2019, in Wuhan (China), SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) was described for the first time [1]. This novel type of coronavirus spread rapidly through global population in few months with raising concern among public and health authorities worldwide until the World Health Organization (WHO) declared pandemic status on 11th March 2020 [2]. SARS-CoV-2 is the etiologic…

Psychodermatology and Psoriasis

Download as PDF INTRODUCTIONPsoriasis is an immune-mediated chronic inflammatory skin disease affecting 2-3% of the adult population globally [1-3]. Chronic plaque psoriasis is characterised by pruritic, well-demarcated, pink plaques (in lighter skin) or grey plaques (in darker skin) covered in silvery scale [1]. There is a strong genetic susceptibility to developing psoriasis with genome-wide association studies reporting over 80 risk…

Psychodermatology and Psoriasis

INTRODUCTION Psoriasis is an immune-mediated chronic inflammatory skin disease affecting 2-3% of the adult population globally [1-3]. Chronic plaque psoriasis is characterised by pruritic, well-demarcated, pink plaques (in lighter skin) or grey plaques (in darker skin) covered in silvery scale [1]. There is a strong genetic susceptibility to developing psoriasis with genome-wide association studies reporting over 80 risk loci, resulting…

How to improve people-centred healthcare in dermatology?

Download as PDF BackgroundPsoriasis is a chronic inflammatory skin disease characterised by extensive redness and thick scales on the skin, usually accompanied by a painful and itchy skin, leading to a high level of suffering and a decades to life-long course impairment. Its prevalence varies in different geographic areas from 0.14% to 2.5% [1]. Relevant cardiovascular and metabolic comorbidities have…

Psychodermatology and Psoriasis

Download as PDF INTRODUCTIONPsoriasis is an immune-mediated chronic inflammatory skin disease affecting 2-3% of the adult population globally [1-3]. Chronic plaque psoriasis is characterised by pruritic, well-demarcated, pink plaques (in lighter skin) or grey plaques (in darker skin) covered in silvery scale [1]. There is a strong genetic susceptibility to developing psoriasis; over 80 risk loci have been identified by…

Psoriasis and COVID-19: findings from PsoProtectMe.

Download as PDF INTRODUCTIONThe COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), heralded an unprecedented era in healthcare[1]. There was global concern amongst both the clinical and scientific communities about the immediate and longer-term health implications of COVID-19 in the general population. Risk factors for poor COVID-19 outcomes were uncovered early in the pandemic using population-level studies,…

Pathogenesis of Psoriatic Arthritis

Download as PDF INTRODUCTIONPsoriatic Arthritis (PsA) is defined as an inflammatory arthritis associated with cutaneous psoriasis, and is classified according to the Classification of PsA criteria (CASPAR)[1]. PsA is a heterogeneous disease: manifestations include synovitis, enthesitis, dactylitis, axial arthritis in addition to skin and nail psoriasis. These manifestations may not be present in all patients and can vary with time[2]….

SARS-CoV-2 vaccination management in patients with chronic plaque psoriasis

Download as PDF IntroductionIn December 2019, in Wuhan (China), SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) was described for the first time [1]. This novel type of coronavirus spread rapidly through global population in few months with raising concern among public and health authorities worldwide until the World Health Organization (WHO) declared pandemic status on 11th March 2020 [2]. SARS-CoV-2…

Inflammatory diseases – a new way of thinking

Download as PDF IntroductionThe treatment of psoriasis has made tremendous progress over the last two decades and has become seemingly simple. A number of therapeutic biologics have been developed that causally intervene by blocking certain cytokines in the immunological cascade of the T-cell mediated autoimmune response of psoriasis. Thus, depending on the drug, an injection given at intervals of 2…






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